接ビーコンを利用した屋内位置測位手法を提案する．従来, 受信信号強度を利用する屋内位置測位としては, 三点測

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Regardless of all latest therapeutic improvements, a proportion of sufferers will nonetheless fail to respond and should be deemed for curative therapy. At the moment, only allogeneic hematopoietic mobile transplantation is usually thought of most likely curative, but It is usually connected to appreciable morbidity and mortality. In the last many years, the amount of individuals referred for allogeneic hematopoietic cell transplantation has dropped noticeably,133 though the technique need to be advisable to younger/match people in whom BCR/BCL2 inhibitor procedure fails, specifically in These with TP53 aberrations, or in the situation of Richter transformation.

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アクセスポイントへの帯域割り当てと端末の接続先アクセスポイントの変更を行い，ネットワーク性能を向上させる

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Treatment for relapsed/refractory sickness needs to be resolved based upon prior therapy in addition to The key reason why why the initial treatment method was not suitable (e.g., refractoriness vs. intolerance). Ibrutinib is the current gold conventional therapy for clients with relapsed/refractory ailment, depending on the outcomes of several section I-III trials, a hundred and fifteen–119 but That is also modifying for two most important good reasons: (i) an increasing proportion of people at this time obtain ibrutinib as frontline therapy; and (ii) a few really serious contenders have appeared in the last 12 months.

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Not all people with CLL require therapy. In spite of all recent improvements, the iwCLL however endorses watchful observation for people with asymptomatic disease.86 This recommendation is based on a minimum of two randomized trials comparing observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Equally trials concluded that early therapy in asymptomatic sufferers was not linked to a chronic Over-all survival.